Abstract: Many examples of chemical and biological processes take place in large-scale environmental flows. Such flows generate filamental patterns which are often fractal due to the presence of chaos in the underlying advection dynamics. I will present a simple and universally valid approach for the activity in inhomogeneous flows. I will derive a rate equation which is universal in the sense that is independent of the flow, of the particle properties, and of the details of the active process. I will show that the fractal patterns serve as skeletons and catalysts, and as a result, the production is singularly enhanced.